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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD2
All Species:
3.33
Human Site:
T781
Identified Species:
12.22
UniProt:
Q9BYW2
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYW2
NP_054878.5
2564
287550
T781
V
V
K
E
P
V
D
T
R
V
S
C
C
K
T
Chimpanzee
Pan troglodytes
XP_516423
2549
285788
K774
R
V
S
C
C
K
T
K
D
S
D
I
Y
C
T
Rhesus Macaque
Macaca mulatta
XP_001113652
2550
286209
R767
V
K
E
P
V
D
T
R
V
S
C
C
K
T
K
Dog
Lupus familis
XP_864158
2562
287091
M778
V
I
K
E
P
V
D
M
T
V
S
C
C
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418510
2354
262767
S641
E
S
T
E
D
P
N
S
K
S
A
C
E
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783359
3042
342758
E840
F
K
I
D
Q
E
S
E
S
D
S
G
A
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2LAE1
1759
193210
S46
S
R
G
Q
N
L
D
S
V
S
S
L
E
I
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.9
92
N.A.
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.7
Protein Similarity:
100
98.9
98
94.6
N.A.
N.A.
N.A.
N.A.
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
41.6
P-Site Identity:
100
13.3
13.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
20
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
15
0
15
0
0
% A
% Cys:
0
0
0
15
15
0
0
0
0
0
15
58
29
15
0
% C
% Asp:
0
0
0
15
15
15
43
0
15
15
15
0
0
0
0
% D
% Glu:
15
0
15
43
0
15
0
15
0
0
0
0
29
15
15
% E
% Phe:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
0
0
0
15
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
15
0
0
0
0
0
0
0
0
15
0
15
0
% I
% Lys:
0
29
29
0
0
15
0
15
15
0
0
0
15
29
15
% K
% Leu:
0
0
0
0
0
15
0
0
0
0
0
15
0
0
15
% L
% Met:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
15
0
15
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
15
29
15
0
0
0
0
0
0
0
0
15
% P
% Gln:
0
0
0
15
15
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
15
0
0
0
0
0
15
15
0
0
0
0
0
0
% R
% Ser:
15
15
15
0
0
0
15
29
15
58
58
0
0
0
0
% S
% Thr:
0
0
15
0
0
0
29
15
15
0
0
0
0
15
43
% T
% Val:
43
29
0
0
15
29
0
0
29
29
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _